St. Elizabeth Ann Seton Catholic School stresses a solid basic curriculum, offering a strong foundation for higher level subjects. The curriculum includes Catholic religious studies, mathematics, language arts, science, social studies, library, Spanish, art, technology, physical education and music.
The curriculum is in compliance with that specified by the Office of Education of the Diocese of St. Augustine and the State of Florida.
St. Elizabeth Ann Seton Catholic School is accredited by the Florida Catholic Conference, affiliated with the National Catholic Education Association and the Florida Association of Academic Non-Public Schools.